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I-4 ULTIMATE
The "I-4 Ultimate" construction project is over budget and behind schedule, according to a Moody's Investor Service report. Florida transportation officials denies the timetable or budget have changed. (Erin Murray, staff)
By Erin Murray | July 12, 2018 @3:32 PM
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ORLANDO, Fla. -- The "I-4 Ultimate" project is behind schedule and over budget, an investment ratings report says -- which could mean commuters driving in construction zones for months longer than expected.

The recently released report, put together by Moody's Investor Service, downgraded the I-4 Ultimate project's outlook from stable to negative.

That is very concerning to the private investors, who are part of the public-private partnership that funds the project to widen and improve almost two dozen miles of Interstate 4 in the Central Florida area.

But along with the investors, regular drivers are also expressing their concern.

"It's horrible, yes. I said it... it is horrible," driver Keysi Quezada said. "It is going to be a pain for people who are traveling back and forth."

The report determined that the I-4 Ultimate project is behind schedule by eight months, estimating a 245-day delay in completion. On top of that, the report says concessionaire I-4 Mobility Partners is asking the Florida Department of Transportation for $100 million in additional compensation.

More delays and budget issues with the are revealed in an investors service report. says the project is 245 days behind schedule backers are seeking $100 million more in compensation.

The Moody's report says the reason for the delays and need for more money comes from drilled shaft failures and flooding, which has led to foundation issues.

Florida transportation officials insisted Thursday that the time frame and budget for the project have not changed.

"The I-4 Ultimate project remains on budget, and the final completion time period of early 2021 remains the same."

As for the concessionaire's request for more money, FDOT said that's still under review.

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PLANT LECTINS

The high toxicity of castor beans was recognized during the last century when the extract was found to agglutinate a suspension of erythrocytes of different animal species. Since then, lectins were studied and extracted from plants, including fungus and lichens, as well as in animals.

Lectins are glycoproteins of 60,000-100,000 MW that are known for their ability to agglutinate (clump) erythrocytes in vitro. There are over 400,000 estimated binding sites for kidney bean agglutinin on the surface of each erythrocytes. Lectins are found in most types of beans, including soybeans. Reduced growth, diarrhea, and interference with nutrient absorption are caused by this class of toxicants. Different lectins have different levels of toxicity, though not all lectins are toxic, though no all are toxins. The bright scarlet seeds of precatory bean Abrus precatorius contain the highly toxic glycoprotein, abrin. Less toxic lectins can be fatal if ingested in high amounts. Some of such lectins is concanavalin A from Concanavalia ensiformis (jack bean). Others may exhibit no hemagglutinating activity as in the case of ricin from castor bean and yet it is one of the most toxic substances.

The terms phytohemagglutinins, phytagglutinins, and lectins are used interchangeably. Lectins-containing plants have been found in many botanical groups including mono- and dicotyledons, molds and lichens, but most frequently they have been detected in Leguminoseae and Euphorbiaceae. They may exist in various tissues of the same plant and have different cellular localizations and molecular properties.

Lectins interaction with certain carbohydrate is very specific. This interaction is as specific as the enzyme-substrate, or antigen-antibody interactions. Lectins may bind with free sugar or with sugar residues of polysaccharides, glycoproteins, or glycolipids which can be free or bound (as in cell membranes). The term lectin refers to the specificity of the reaction (legere = to choose).

One of the major interest in this class of glycoproteins is the therapeutic use against HIV-1. Jacalin, a plant lectin, is found to completely block human immunodeficiency virus type 1 in vitro infection of lymphoid cells. This activity of the jacalin is attributed to its ability to specifically induce the proliferation of CD4+ T lymphocytes in human.

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The ability to agglutinate human erythrocytes or representatives of human indigenous microflora was detected in 29 of 88 food items. Many foods contained substantial amounts of agglutinating activity, and lectins extracts could be diluted several folds and still produce agglutination. Great variation was observed in agglutination activity in the same food item purchased from different stores or from the same store on different days. Sometimes a food that possessed substantial activity on one day was found to have little or even no activity on other day.

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Join us for OLC Accelerate! November 14-16, 2018 The Walt Disney WorldSwan and Dolphin Orlando, FL • Clearance Lowest Price Shopping Online cut out shoulder top Pink amp; Purple Pinko Choice Online 1NbdpH

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Join us for a special half-day event in collaboration with senior digital learning leaders to address the biggest challenges we face today in higher education.

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Join us for the Global Quality Summit (GQS) as part of the Accelerate conference. In the GQS, you will have opportunities to learn, discuss and share best practices in online and digital learning with high level representatives from global institutions.

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ABOUT OLC ACCELERATE

In 2018, you won’t be able to have a dialogue about higher education without discussing, in part, online learning. It’s one of the fastest growing sectors in education today, and as the pace of growth accelerates, we’d like to invite you to OLC Accelerate, the premier global gathering covering this field.

We chose the name OLC Accelerate because this conference is devoted to driving quality online learning, advancing best practice guidance and accelerating innovation in learning for academic leaders, educators, administrators, online learning professionals and organizations around the world.

Following the success of 2017’s OLC Accelerate, the 2018 conference will be the ultimate event to network with—and learn from—thousands of your eLearning peers.

As always, this international conference promises outstanding keynote speakers, expanded programs, and engaging workshops. Our ever popular Technology Test Kitchen and Discovery sessions will once again deliver the opportunity to interact with experts in new and emerging eLearning technologies and topics, reinforcing why online educators worldwide affirm that OLC Accelerate is the premiere conference for online learning professionals.

Our curation of conference tracks and exhibits promises a cross section of timely eLearning topics, offering something for everyone involved in providing the highest quality educational experiences in 2018.

Join us in our commitment to accelerate online learning worldwide. We look forward to connecting with you in Orlando, November 14-16, 2018.

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We are interested in proposals for interactive sessions for Pre-conference Workshops, Discovery Sessions, Panel Discussions, Express Workshops, Global Quality Summit Sessions, and EducationSessions that engage and inform participants.

Proposed sessions will be targeted to all attendees or novice, intermediate, or expert levels of proficiency.

Presenters and facilitators from the following areas were encouraged to submit proposals:

Higher Education • K-12 Faculty • Researchers • Graduate Scholars • Educational Technology Leaders • Instructional designers • Instructional Technologists • Faculty • Instructors

OLC Accelerate 2018Call For Presentations

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